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Fig. 4 | Molecular Cancer

Fig. 4

From: Mechanism of ERBB2 gene overexpression by the formation of super-enhancer with genomic structural abnormalities in lung adenocarcinoma without clinically actionable genetic alterations

Fig. 4

Integrated visualization of Hi-C and ChIP-seq data. A Table summary of the case used in the integrated analysis of Hi-C and ChIP-seq. B-D The displayed region on chromosome 17, which covers positions 37,034,000 to 40,422,000, lies between the HNF1β and ERBB2 gene loci. The region enclosed by the green dashed line indicates the proximity of the HNF1β and ERBB2 gene loci. The case shown in panel D was used as a negative control in which ERBB2 is not overexpressed. dJapanese PDX [35]. eVerified by IHC and RNA-seq [34]

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Molecular Cancer

ISSN: 1476-4598