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Fig. 1 | Molecular Cancer

Fig. 1

From: Circular RNAs in tumor immunity and immunotherapy

Fig. 1

Roles of circRNAs in the tumor microenvironment. A CircRNAs can as miRNAs sponge to regulate the expression of PD1/PD-L1 and inhabit activation of T cells. B CircRNAs can bind to miRNAs to influence the NK cell-mediated killing ability and cytotoxicity. C Exogenous circRNAs can regulate the function of antitumor immunity in RIG-dependent manner. D Exo-circRNAs can regulate antitumor immunity. ciRNAs: circular intronic RNAs; ecircRNAs: exonic circRNAs; EIciRNAs: exonic-intronic circRNAs; exo-circRNAs: exosomes circRNAs

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Molecular Cancer

ISSN: 1476-4598