Fig. 3

CircLIFRSA serves as an early diagnostic biomarker for lung cancer. (A) The standard curve was used in absolute quantitation. (B) The expression levels of circLIFRSA in whole blood of healthy people (n = 49), benign lung disease (n = 30), and NSCLC (n = 60) were detected by RT-qPCR. (C) ROC curve of circLIFRSA distinguishing benign lung disease from cancer patients. (D) ROC curve of circLIFRSA distinguishing early stage I from other stages (II-IV) in NSCLC patients.*** P < 0.001