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Fig. 5 | Molecular Cancer

Fig. 5

From: CircLIFRSA/miR-1305/PTEN axis attenuates malignant cellular processes in non-small cell lung cancer by regulating AKT phosphorylation

Fig. 5

CircLIFRSA interacts and negatively correlates with miR-1305. (A) MiR-1305 was predicted to interact with circLIFRSA through bioinformatic analysis. (B) MiR-1305 binds with wild-type (WT) circLIFRSA via core miRNA recognition element, but not mutated (MUT) circLIFRSA. (C) MiR-1305 was highly expressed in NSCLC cells. (D) MiR-1305 was downregulated upon circLIFRSA overexpression. (E-H) MiR-1305 was highly expressed in tumor tissues compared to adjacent tissues in patients with NSCLC. (I) CircLIFRSA was negatively correlated with miR-1305 in patients with NSCLC. ** P < 0.01

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Molecular Cancer

ISSN: 1476-4598