Fig. 2

Development trends and future directions in the AlphaFold domain. (A) Regression curve analysis reveals the correlation between the annual occurrence frequency of research hotspots and publication time. ‘s’ represents the slope of the fitted curve, ‘R2’ represents the coefficient of determination, and ‘CI’ represents the confidence interval. (B) Hotspot burst analysis for global research hotspots of AlphaFold model. (C) The graph-based community detection algorithm Walktrap reveals the critical but still underdeveloped directions for this field that deserve further research. The X-axis represents the relevance to the field, and the Y-axis represents the relative development degree