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Fig. 1 | Molecular Cancer

Fig. 1

From: Size matters: integrating tumour volume and immune activation signatures predicts immunotherapy response

Fig. 1

Tumour volume-normalised immune gene sets predict ICI response. A) Receiver operator characteristic (ROC) curves measuring the ICI predictive performance of each indicated immune-associated transcriptome gene sets with and without tumour volume normalisation (ssGSEA scores divided by total tumour volume) in melanoma tumours prior to treatment with combination ICIs (n = 32). B) ROC curves of Hallmark Interferon Gamma (IFNγ) Response gene set with and without tumour volume normalisation in melanoma tumours prior to treatment with PD-1 ICI (n = 23).

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Molecular Cancer

ISSN: 1476-4598