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Fig. 3 | Molecular Cancer

Fig. 3

From: Chimeric antigen receptor macrophages targeting c-MET(CAR-M-c-MET) inhibit pancreatic cancer progression and improve cytotoxic chemotherapeutic efficacy

Fig. 3

A CAR THP-1 or NC THP-1 and BxPC-3 luci + cells were co-cultured for 24 h at different E: T ratios and bioluminescence imaging was performed in the co-culture system. B CAR THP-1 or NC THP-1 and BxPC-3 luci + cells were co-cultured at 5:1 for different times, and bioluminescence imaging was performed in the co-culture system. C CAR THP-1 or NC THP-1 and BxPC-3 were co-cultured for 24 h at different E: T ratios, and LDH content in the supernatant of the co-culture system was detected. D The co-culture system was photographed by fluorescence confocal microscope, and the process of macrophages extending pseudopodia, endocytosis, and lysis of BxPC-3 cells.(**, p < 0.01;***, p < 0.001)

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Molecular Cancer

ISSN: 1476-4598