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Fig. 8 | Molecular Cancer

Fig. 8

From: Chimeric antigen receptor macrophages targeting c-MET(CAR-M-c-MET) inhibit pancreatic cancer progression and improve cytotoxic chemotherapeutic efficacy

Fig. 8

A, B hMDM-UTD,hMDM-Adv,hMDM-CAR coculture with BxPC-3, Mia Paca 2,PANC-1 cell for 6 h or 12 h at a ratio of 1:3. C hMDM-UTD,hMDM-Adv and hMDM-CAR-HER2 coculture with BxPC-3 and N87 for 12 h at a ratio of 1:3. D BxPC-3, N87 HER2 expression detection. E the dynamic tumor burden after different treatments. F the biodistribution of hMDM-CAR after i.p. G CAR-c-MET-hMDM could prolong the survival of the orthotopic tumor bearing mice

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