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Editorial expression of concern: Withanolide D induces apoptosis in leukemia by targeting the activation of neutral sphingomyelinase-ceramide cascade mediated by synergistic activation of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase
Molecular Cancer volume 24, Article number: 103 (2025)
The Original Article was published on 13 September 2010
Correction: Mol Cancer 9, 239 (2010)
The Editor-in-Chief is issuing this editorial expression of concern to inform the readers that following the publication of the article, concerns were raised regarding multiple image similarities found in Figs. 1B and E and 2C, 3 A, 4 A, 5 A, and 7E. Due to the age of the article, the authors were unable to provide all concerned raw data files. An investigation by the publisher found evidence of image editing that was not transparently stated in the article. Additionally, the flow cytometry plot in Fig. 1e shows repetitive data point patterns, which are unlikely to occur naturally in this type of data. Similarly, the background of the blot presented in Fig. 2c appears to show repetitive non-specific markings.
Therefore readers are alerted to interpret this data with caution.
Author, Chitra Mandal agrees with this Editorial Express of Concern. The Publisher is unable to get current email addresses for authors, Susmita Mondal, Chandan Mandal, Rajender Sangwan, and Sarmila Chandra.
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The online version of the original article can be found at https://doiorg.publicaciones.saludcastillayleon.es/10.1186/1476-4598-9-239.
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Mondal, S., Mandal, C., Sangwan, R. et al. Editorial expression of concern: Withanolide D induces apoptosis in leukemia by targeting the activation of neutral sphingomyelinase-ceramide cascade mediated by synergistic activation of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase. Mol Cancer 24, 103 (2025). https://doiorg.publicaciones.saludcastillayleon.es/10.1186/s12943-024-02185-7
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DOI: https://doiorg.publicaciones.saludcastillayleon.es/10.1186/s12943-024-02185-7