Fig. 2
From: Emerging role of exosomes in cancer therapy: progress and challenges
Production of extracellular vesicles. The formation of extracellular vesicles. EVs are membrane-enclosed particles discharged by cells and categorized into exosomes, microvesicles, and apoptotic bodies in accordance with their origin and size. Exosomes are formed within multivesicular bodies and are released when these bodies merge with the plasma membrane. Microvesicles sprout directly from the plasma membrane, while apoptotic bodies arise from cell fragmentation during apoptosis