Fig. 6

sEVs in anti-cancer therapy. Depleting tumor-derived exosomes (TDEs) through methods like inhibiting their production, filtering them from circulation, or blocking their interaction with cells could disrupt neoplastic progression. sEVs also serve as effective drug delivery vectors. With enhanced permeability and retention (EPR) effects, the ability to traverse biological barriers, and reduced immunogenicity, sEVs can efficiently deliver anticancer medications to target cells for both single therapy and combination therapy. Reproduced from ref. 75 with permission from Elsevier copyright 2021