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Fig. 5 | Molecular Cancer

Fig. 5

From: DNA damage response signatures are associated with frontline chemotherapy response and routes of tumor evolution in extensive stage small cell lung cancer

Fig. 5

Association between DDR status and frontline chemotherapy response. A Maximum sum of longest dimensions (SLD) change for IMpower133 DDR clusters following frontline EP chemotherapy. B RECIST Best Overall Response (BOR) for IMpower133 DDR clusters following frontline EP chemotherapy. NR: Non-responder (progressive disease + stable disease). R: Responder (partial response + complete response). C Kaplan Meier plot for IMpower133 SCLC-A DDR cluster OS outcomes following frontline EP chemotherapy. D Forrest plot for IMpower133 SCLC-A DDR cluster OS outcomes following frontline EP chemotherapy

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