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Table 2 Pathological complete response

From: Perioperative nivolumab and chemotherapy in locally advanced squamous cell carcinoma of the oesophagus: a randomized multicentre phase 2 study with circulating tumor DNA dynamics monitoring

 

Nivo + chemo

Chemo

 

outcomes

(n = 60)

(n = 30)

p

pCR

9

4

0.832

pCR rate, % (95% CI) a

15 (7.1–26.57)

13.33 (3.76–30.72)

 

Rate-diff, % (95% CI) b

1.67 (-16.08–15.37)

 

RR (95% CI)

1.13 (0.38–3.36)

 

ypT0

11

6

0.849

ypT0 rate, % (95%CI) a

18.33 (9.52–30.44)

20.00 (7.71–38.57)

 

MPR

20

10

1

MPR rate, % (95%CI) a

33.33 (21.69–46.69)

33.3 (17.29–52.81)

 
  1. Abv: pCR, pathological complete response; CI, confidence interval; RR, relative risk; MPR, major pathological response
  2. a. Clopper-Pearson method
  3. b. Newcombe-Wilson method