Skip to main content

Table 3 Pathological outcomes

From: Perioperative nivolumab and chemotherapy in locally advanced squamous cell carcinoma of the oesophagus: a randomized multicentre phase 2 study with circulating tumor DNA dynamics monitoring

 

Nivo + chemo

Chemo

 

outcomes

(n = 55)

(n = 30)

p

R0 resection (%)a

53 (96.4)

29 (96.6)

1

Tumor regression gradea

   

1 (Residual tumor 0)

11 (20)

6 (20)

0.688

2 (Residual tumor 1–10%)

9 (16.4)

5 (16.7)

3 (Residual tumor 11–50%)

12 (21.8)

4 (13.3)

4 (Residual tumor > 50%)

23 (41.8)

15 (50)

Lymph nodes involvedb

   

ypN0

38 (69.1)

13 (43.3)

0.021*

ypN+

17 (30.9)

17 (56.7)

ypTNM stageb

   

I

27 (49.1)

11 (36.7)

0.088

II

11 (20)

2 (6.7)

III

15 (27.3)

14 (46.6)

IV

2 (3.6)

3 (10)

  1. a. Chi-square test
  2. b. Fisher exact probability test