Fig. 1
From: Dissecting small cell carcinoma of the esophagus ecosystem by single-cell transcriptomic analysis
Single cell landscape of immune, stroma and epithelial cells of esophageal comparative cohorts. A Scheme of the overall study design. B UMAP visualization of the major cell clusters including 197,858 high-quality single cells from 42 samples collected from 31 candidates (10 HCs, 11 pts with ESCC, 10 pts with SCCE). C Box and whisker plots showing the fraction of cell types originating from four groups in each major cell cluster with plot center, box and whiskers corresponding to median, interquartile range (IQR) and 1.5 × IQR, respectively (*P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001). D UMAP plots, as shown in (B), showing TME cell clusters and cell distribution density (shown as thermodynamic chart) across different tissue groups