Fig. 3
From: Multimodal lung cancer theranostics via manganese phosphate/quercetin particle
In vitro treatment effects of AHA@MnP/QCT NPs. (A-B) Relative viabilities of Lewis cells aftertreatment with different concentrations of QCT and nanoplexes for 48 h (n = 6); (C) TEM imaging of the formation of apoptotic bodies with aftertreatment of AHA@MnP/QCT NPs (red arrows: NPs uptake; yellow box: apoptotic vesicle exocytosis); (D) Flow cytometry analysis of Annexin V-FITC/PI costained Lewis cells; (E) Quantitative analysis the apoptosis rate of Lewis cells; (F) PI/Calcein-AM double staining images of Lewis cells; (G) The expression of P-Caspase-3, Bcl-2 and Bax protein for Lewis cells treated with QCT, AHA@MnP or AHA@MnP/QCT NPs