Fig. 6
From: Multimodal lung cancer theranostics via manganese phosphate/quercetin particle
Mechanisms of immunogenic cell death in AHA@MnP/QCT NPs. (A) The expression of cGAS, p-STING and STING protein for dendritic cells treated with AHA@MnP or AHA@MnP/QCT NPs; (B) Quantitative analysis the protein intensity rate of dendritic cells. Data are presented as the mean ± SD (n = 3); (C) Intracellular ATP level for Lewis cells treated with AHA@MnP NPs or AHA@MnP/QCT NPs; (D) Intracellular HMGB1 level for Lewis cells treated with AHA@MnP NPs or AHA@MnP/QCT NPs. ****P < 0.001, ***P < 0.001, **P < 0.01, *P < 0.05 (E) Confocal images of CRT expression in Lewis cells pretreated with AHA@MnP NPs or AHA@MnP/QCT NPs (Scale bar: 50 μm)