Fig. 7
From: Multimodal lung cancer theranostics via manganese phosphate/quercetin particle
In vivo antitumor effect of AHA@MnP/QCT NPs. (A) Scheme illustration for the in vivo evaluation of antitumor therapy; (B) The images for Lewis’s tumor bearing mice treated with AHA@MnP or AHA@MnP/QCT NPs; (C)Tumor growth curves of the mice treated with different samples. n = 5, ****P < 0.0001, ***P < 0.001; (D) Digital photos of excised tumors from the mice at day 12. (E) Survival curves analysis; (F) Immunofluorescence was used to examine CD11C+, CD4+, CD8+, Fopx3+, CD80 + and CD206 + in tumor sections. Scale bar = 50 μm; (G) Tumor weight analysis; (H-M) Fluorescence intensity of tumors calculated based on part (F) using ImageJ. The results are expressed as mean and SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001; (N) Scheme illustration for AHA@MnP/QCT NPs involved in the immunotherapy process